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In the only study we found that required histologic confirmation of alcoholic hepatitis in all patients, prednisolone was associated with a short-term reduction in mortality, but this benefit was not apparent after 2 years.

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While prednisolone is often substituted for dexamethasone when the latter is unavailable, the efficacy of prednisolone has never been directly compared with dexamethasone.

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In those without a previous fracture and a T score above 0, reassurance and general measures are advised, and repeat BMD measurement is not indicated unless exceptionally high doses of glucocorticoids are required, as in for instance intravenous methyl prednisolone protocols.

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Of note, direct inhibition of autoantibody production was only seen at the higher dose of MMF, whereas qualitative changes with a reduction in total and antigen-specific IgG2a were seen at the lower dose of MMF, suggesting that this might be one of the mechanisms resulting in disease amelioration.

Betamethasone; cortisone; dexamethasone; hydrocortisone; methylprednisolone; prednisolone; prednisone; and triamcinolone are indicated for treatment of severe cases not controlled by antimyasthenic agents alone.

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